Five peach aphid（Myzus persicae）populations were collected from vegetable fields in Shouguang，Jinan，Tai’an，Yantai，and Linyi locations of Shandong province to test their sensitiveness to commonly used acetamiprid and imidacloprid．The results indicated that Myzus persicae populations from different locations of Shandong Province had different levels of resistance to acetamiprid and imidacloprid，except population from Yantai was sensitive to Imidacloprid．Compared with the sensitive population，Tai’an population appeared to have the highest LC₅₀ for acetamiprid（451.264 1 mg·L^-1）with resistance ratio 23.63 fold．The highest resistance level to imidacloprid was recorded in Linyi，and the LC₅₀ amounted to 317.944 6 mg·L^-1 with resistance ratio 14.40．These 2 insecticides had not shown high and higher level drug resistance．In actual peach aphid control，we should pay attention to rotate application of other type insecticides.