Abstract：Since the 20th century 90’s, genetic engineering technology has been used to cultivate new cucumber（Cucumis sativus L.）variety. To certain extent this has broken the reproductive isolation between bioses and made cucumber breeding with clearer objectives. At the same time, it has also solved problems existing in traditional cucumber breeding, such as longer cycle, narrow germplasm resources and lack of germplasm resources with useful characteristics. This review summarized the progress made in transgenic cucumber, such as disease-tolerance, insect-tolerance, stress-tolerance, quality, herbicide tolerance, parthenocarpic fruits and yield, etc. It also discussed about the huge commercial potential in cucumber, pointed out the aims of transgenic cucumber in recent years. This review also focused on other issues like biology safety and commercialization of transgenic cucumber. It carries out discussion on transgenic cucumber food and bio-safety strategy.