Taking organically cultured tomato variety‘ Xianke No.8’ as experimental material and adopting two factor randomized block design，this paper studied the effect of‘ Pulyutong’ plant immune protein on tomato growth，yield，quality，and disease resistance under organic cultivation condition in early spring solar
greenhouse. The results show that compared with the treatment without‘ Pulyutong’ plant immune protein，the growth，yield，quality，and disease resistance of applying‘ Pulyutong’ plant immune protein were all improved. The yield under T3 treatment compared with the control，increased by 74.08% ，VC content and sugar-acid ratio increased by 61.9 mg·kg-1 and 3.94，respectively. While，the fruit-dropping rate and irregular-fruit-rate were reduced by 8.66 and 19.16 percentage points，respectively，and yet no dead plant，virus disease and bacteria wilt were reported. So，we recommended to adopt  application of‘ Pulyutong’ plant immune protein during the whole growing period since the seedling stage，T3 treatment was the best choice.